Hiroko Tsutsui Selected Research

Cytokines

2/2015	Caspases as the key effectors of inflammatory responses against bacterial infection.
1/2015	Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.
1/2015	Interleukin-1 Family Cytokines in Liver Diseases.
4/2013	Fas-mediated inflammatory response in Listeria monocytogenes infection.
1/2012	Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors.
1/2010	The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice.
4/2009	Role of ASC in the mouse model of Helicobacter pylori infection.
6/2008	Vaginal infection with Ureaplasma urealyticum accounts for preterm delivery via induction of inflammatory responses.
1/2006	Plasma interleukin (IL)-18 (interferon-gamma-inducing factor) and other inflammatory cytokines in patients with gouty arthritis and monosodium urate monohydrate crystal-induced secretion of IL-18.
8/2005	Endogenous interleukin-6, but not tumor necrosis factor alpha, contributes to the development of toll-like receptor 4/myeloid differentiation factor 88-mediated acute arthritis in mice.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hiroko Tsutsui Research Topics

Disease

17	Infections 01/2019 - 10/2002
15	Inflammation (Inflammations) 12/2017 - 08/2002
6	Atopic Dermatitis (Atopic Eczema) 01/2011 - 08/2002
4	Bacterial Infections (Bacterial Infection) 01/2017 - 08/2005
4	Asthma (Bronchial Asthma) 07/2011 - 12/2004
4	Dermatitis 06/2010 - 08/2002
3	Obesity 12/2017 - 08/2016
3	Respiratory Hypersensitivity 07/2011 - 12/2004
3	Graft vs Host Disease (Graft-Versus-Host Disease) 11/2004 - 07/2002
2	Fibrosis (Cirrhosis) 11/2019 - 01/2015
2	Non-alcoholic Fatty Liver Disease 01/2019 - 08/2016
2	Insulin Resistance 12/2017 - 08/2016
2	Contact Dermatitis (Eczema, Contact) 11/2014 - 07/2008
2	Wounds and Injuries (Trauma) 05/2014 - 08/2009
2	Hepatitis 05/2014 - 01/2013
2	Colitis 06/2013 - 01/2012
2	Necrosis 01/2013 - 03/2010
2	Neoplasms (Cancer) 09/2010 - 03/2002
2	Hypothermia 03/2010 - 01/2010
2	Shock 03/2010 - 11/2002
2	Rheumatoid Arthritis 08/2005 - 12/2003
2	Arthritis (Polyarthritis) 08/2005 - 12/2003
2	Skin Diseases (Skin Disease) 05/2003 - 08/2002
1	Tissue Adhesions 01/2019
1	Pneumococcal Pneumonia 01/2019
1	Body Weight (Weight, Body) 12/2017
1	Rupture 01/2015
1	Aortic Aneurysm (Aneurysm, Aortic) 01/2015
1	Liver Diseases (Liver Disease) 01/2015
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2015
1	Glomus vagale tumors 10/2014
1	Acute Liver Failure (Fulminant Hepatic Failure) 05/2014
1	Thrombophilia 05/2014
1	Reperfusion Injury 05/2014
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2014
1	Sarcoma (Soft Tissue Sarcoma) 01/2014
1	Ewing Sarcoma (Sarcoma, Ewing) 01/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014
1	Liposarcoma 01/2014

Drug/Important Bio-Agent (IBA)

23	Interleukin-18 (Interleukin 18)IBA 05/2013 - 03/2002
17	CytokinesIBA 02/2015 - 08/2002
7	InflammasomesIBA 01/2019 - 05/2010
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013 - 12/2003
6	Interleukin-6 (Interleukin 6)IBA 11/2019 - 03/2002
5	Proteins (Proteins, Gene)FDA Link 01/2017 - 07/2010
4	Interleukin-12 (IL 12)IBA 03/2007 - 10/2002
3	Glucose (Dextrose)FDA LinkGeneric 12/2017 - 08/2016
3	TeaIBA 12/2017 - 01/2014
3	AntigensIBA 11/2014 - 12/2004
3	Fas Ligand Protein (Fas Ligand)IBA 04/2013 - 10/2002
3	Interleukin-13IBA 02/2012 - 07/2010
3	ChemokinesIBA 01/2012 - 03/2007
3	Interleukin-8 (Interleukin 8)IBA 12/2011 - 01/2006
2	Caspase 1 (ICE Protease)IBA 02/2015 - 02/2004
2	Interleukin-1 (Interleukin 1)IBA 01/2015 - 08/2002
2	Interleukin-33IBA 01/2015 - 02/2012
2	Concanavalin AIBA 05/2014 - 01/2013
2	LipopolysaccharidesIBA 05/2014 - 12/2011
2	Double-Stranded RNA (RNA, Double Stranded)IBA 06/2013 - 07/2011
2	InterferonsIBA 06/2013 - 01/2013
2	Interferon-gamma (Interferon, gamma)IBA 01/2013 - 08/2005
2	OvalbuminIBA 07/2011 - 07/2010
2	Staphylococcal Protein A (Protein A)IBA 07/2010 - 05/2003
2	NF-kappa B (NF-kB)IBA 05/2010 - 08/2003
2	Toll-Like Receptors (Toll-Like Receptor)IBA 08/2005 - 10/2002
2	Myeloid Differentiation Factor 88IBA 08/2005 - 10/2002
2	Interleukin-18 ReceptorsIBA 03/2004 - 07/2002
2	EndotoxinsIBA 08/2003 - 11/2002
2	Immunoglobulin E (IgE)IBA 05/2003 - 08/2002
1	Caffeine (No Doz)FDA LinkGeneric 01/2019
1	Transcription Factors (Transcription Factor)IBA 01/2019
1	CollagenIBA 01/2019
1	Insulin (Novolin)FDA Link 12/2017
1	Fatty Acids (Saturated Fatty Acids)IBA 12/2017
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2017
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2017
1	LipidsIBA 11/2016
1	AntioxidantsIBA 08/2016
1	CaspasesIBA 02/2015
1	Caspase 8 (Caspase-8)IBA 02/2015
1	AlarminsIBA 01/2015
1	Apolipoproteins E (ApoE)IBA 01/2015
1	Angiotensin IIIBA 01/2015
1	IntegrinsIBA 11/2014
1	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 11/2014
1	Cullin Proteins (Cullins)IBA 10/2014
1	Ligases (Synthetase)IBA 10/2014
1	TATA-Box Binding Protein (TATA-Binding Protein)IBA 01/2014
1	CopperIBA 01/2014
1	ZincIBA 01/2014
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2014
1	Superoxide DismutaseIBA 01/2014
1	Thromboplastin (Tissue Factor)IBA 01/2013
1	AnticoagulantsIBA 01/2013
1	Monoclonal AntibodiesIBA 01/2013
1	Heparin (Liquaemin)FDA LinkGeneric 01/2013
1	FibrinIBA 01/2013
1	Interleukin-5 (Interleukin 5)IBA 02/2012

Therapy/Procedure

4	Therapeutics 09/2010 - 08/2002
2	Stem Cell Transplantation 11/2004 - 05/2004